The purinergic P2X7 receptor is not required for control of pulmonary Mycobacterium tuberculosis infection.
نویسندگان
چکیده
The importance in vivo of P2X7 receptors in control of virulent Mycobacterium tuberculosis was examined in a low-dose aerosol infection mouse model. P2X7(-/-) mice controlled infection in lungs as well as wild-type mice, suggesting that the P2X7 receptor is not required for control of pulmonary M. tuberculosis infection.
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ورودعنوان ژورنال:
- Infection and immunity
دوره 73 5 شماره
صفحات -
تاریخ انتشار 2005